General Information
SPKB ID SPKB07141
Signal sequence MKFSAVSIAAALASLVAA
Length 18
Organism Yarrowia lipolytica JMY2101
UniProt ID NA,
Motif 1..18
Activity Information
Pathway SRP-dependent
Natural/Artificial Artificial
Subcellular location Extracellular environment
Secretion efficiency alpha-amylase yield: 4.35(U/mL)
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB07141.cif
Physicochemical Information
Molecular weight 1721.08814
Aliphatic index 136.1111111
Isoelectric point 9.700002532
Charge (pH=7) 0.997689266
Topological polar surface area 644.73
Aromaticity 0.055555556
Average rotatable bonds 3.055555556
Number of hydrogen bond donors 23
Number of hydrogen bond acceptors 24
X logP energy -5.6688
Hydropathy
Literature Information
Title Robust signal peptides for protein secretion in Yarrowia lipolytica: identification and characterization of novel secretory tags
DOI 10.1007/s00253-018-8966-9,
Publication Year 2018
PubMed ID 29704042,
Patent ID NA,