General Information
SPKB ID SPKB07140
Signal sequence MKVLALLVTVCFSVASA
Length 17
Organism Yarrowia lipolytica JMY2101
UniProt ID NA,
Motif 1..17
Activity Information
Pathway SRP-dependent
Natural/Artificial Artificial
Subcellular location Extracellular environment
Secretion efficiency alpha-amylase yield: 4.84(U/mL)
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB07140.cif
Physicochemical Information
Molecular weight 1752.20384
Aliphatic index 154.7058824
Isoelectric point 8.545189979
Charge (pH=7) 0.93571455
Topological polar surface area 615.63
Aromaticity 0.058823529
Average rotatable bonds 3.294117647
Number of hydrogen bond donors 23
Number of hydrogen bond acceptors 24
X logP energy -3.6029
Hydropathy
Literature Information
Title Robust signal peptides for protein secretion in Yarrowia lipolytica: identification and characterization of novel secretory tags
DOI 10.1007/s00253-018-8966-9,
Publication Year 2018
PubMed ID 29704042,
Patent ID NA,