General Information
SPKB ID SPKB07137
Signal sequence MKFTFAAVTAALASSAMA
Length 18
Organism Yarrowia lipolytica JMY2101
UniProt ID NA,
Motif 1..18
Activity Information
Pathway SRP-dependent
Natural/Artificial Artificial
Subcellular location Extracellular environment
Secretion efficiency alpha-amylase yield: 5.35(U/mL)
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB07137.cif
Physicochemical Information
Molecular weight 1789.13794
Aliphatic index 76.66666667
Isoelectric point 9.700002532
Charge (pH=7) 0.997689266
Topological polar surface area 664.96
Aromaticity 0.111111111
Average rotatable bonds 3.111111111
Number of hydrogen bond donors 24
Number of hydrogen bond acceptors 26
X logP energy -6.6519
Hydropathy
Literature Information
Title Robust signal peptides for protein secretion in Yarrowia lipolytica: identification and characterization of novel secretory tags
DOI 10.1007/s00253-018-8966-9,
Publication Year 2018
PubMed ID 29704042,
Patent ID NA,