SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB07130

Signal sequence   MKFVKRRIIALVTILMLSVTSLFALQPSAKAA

Length  32

Organism  Bacillus subtilis WB800

UniProt ID  NA,

Motif  1..32



Activity Information


Pathway  Tat

Natural/Artificial  Artificial

Subcellular location  Periplasmic space

Secretion efficiency  Lipase yield: 3.31(U/L)

Type  Tat/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB07130.cif

Structure  SPKB07130.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3518.41014

Aliphatic index  140.3125

Isoelectric point  12.54607567

Charge (pH=7)   4.997092575

Topological polar surface area  1302.73

Aromaticity  0.0625

Average rotatable bonds  3.71875

Number of hydrogen bond donors  47

Number of hydrogen bond acceptors  46

X logP energy  -7.72126

Hydropathy 



Literature Information


Title  Effect of Signal Peptide Optimization on Lipase LipS Secretion and Expression in Bacillus subtilis System

DOI  NA,

Publication Year  2015

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.