SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB07128

Signal sequence   MKRLTLVCSIVFILFILFYDLKIGTIPIQDLPVYEASAA

Length  39

Organism  Bacillus subtilis WB800

UniProt ID  NA,

Motif  1..39



Activity Information


Pathway  Sec

Natural/Artificial  Artificial

Subcellular location  Extracellular environment

Secretion efficiency  Lipase yield: 3.93(U/L)

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB07128.cif

Structure  SPKB07128.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  4416.38644

Aliphatic index  150

Isoelectric point  6.37208468

Charge (pH=7)   -0.063616533

Topological polar surface area  1541.85

Aromaticity  0.128205128

Average rotatable bonds  3.641025641

Number of hydrogen bond donors  54

Number of hydrogen bond acceptors  55

X logP energy  -4.29983

Hydropathy 



Literature Information


Title  Effect of Signal Peptide Optimization on Lipase LipS Secretion and Expression in Bacillus subtilis System

DOI  NA,

Publication Year  2015

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.