SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB07127

Signal sequence   MRKVLLLLILLIGLAPTAWAA

Length  21

Organism  Bacillus subtilis WB800

UniProt ID  NA,

Motif  1..21



Activity Information


Pathway  Sec

Natural/Artificial  Artificial

Subcellular location  Extracellular environment

Secretion efficiency  Lipase yield: 4.22(U/L)

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB07127.cif

Structure  SPKB07127.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2276.93874

Aliphatic index  200

Isoelectric point  11.65177567

Charge (pH=7)   1.997685954

Topological polar surface area  760.47

Aromaticity  0.047619048

Average rotatable bonds  3.476190476

Number of hydrogen bond donors  27

Number of hydrogen bond acceptors  26

X logP energy  0.63257

Hydropathy 



Literature Information


Title  Effect of Signal Peptide Optimization on Lipase LipS Secretion and Expression in Bacillus subtilis System

DOI  NA,

Publication Year  2015

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.