SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB07126

Signal sequence   MKKVLMAFIICLSLILSVLAAPPSGAKAA

Length  29

Organism  Bacillus subtilis WB800

UniProt ID  NA,

Motif  1..29



Activity Information


Pathway  Sec

Natural/Artificial  Artificial

Subcellular location  Extracellular environment

Secretion efficiency  Lipase yield: 4.62(U/L)

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB07126.cif

Structure  SPKB07126.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2957.77124

Aliphatic index  148.2758621

Isoelectric point  10.51301932

Charge (pH=7)   2.935124482

Topological polar surface area  999.29

Aromaticity  0.034482759

Average rotatable bonds  3.344827586

Number of hydrogen bond donors  35

Number of hydrogen bond acceptors  39

X logP energy  -4.5407

Hydropathy 



Literature Information


Title  Effect of Signal Peptide Optimization on Lipase LipS Secretion and Expression in Bacillus subtilis System

DOI  NA,

Publication Year  2015

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.