SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB07124

Signal sequence   MKKWLIIAVSLAIAIVLFMYTKGEAKAA

Length  28

Organism  Bacillus subtilis WB800

UniProt ID  NA,

Motif  1..28



Activity Information


Pathway  Sec

Natural/Artificial  Artificial

Subcellular location  Extracellular environment

Secretion efficiency  Lipase yield: 5.12(U/L)

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB07124.cif

Structure  SPKB07124.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3080.86714

Aliphatic index  139.6428571

Isoelectric point  10.4849221

Charge (pH=7)   2.997728873

Topological polar surface area  1066.88

Aromaticity  0.107142857

Average rotatable bonds  3.714285714

Number of hydrogen bond donors  38

Number of hydrogen bond acceptors  39

X logP energy  -1.9515

Hydropathy 



Literature Information


Title  Effect of Signal Peptide Optimization on Lipase LipS Secretion and Expression in Bacillus subtilis System

DOI  NA,

Publication Year  2015

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.