SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB07123

Signal sequence   MRNLTKTSLLLAGLCTAAQMVFVTHASAA

Length  29

Organism  Bacillus subtilis WB800

UniProt ID  NA,

Motif  1..29



Activity Information


Pathway  Sec

Natural/Artificial  Artificial

Subcellular location  Extracellular environment

Secretion efficiency  Lipase yield: 7.68(U/L)

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB07123.cif

Structure  SPKB07123.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3020.61674

Aliphatic index  107.9310345

Isoelectric point  9.834331048

Charge (pH=7)   2.026620329

Topological polar surface area  1202.28

Aromaticity  0.034482759

Average rotatable bonds  3.413793103

Number of hydrogen bond donors  44

Number of hydrogen bond acceptors  44

X logP energy  -13.04853

Hydropathy 



Literature Information


Title  Effect of Signal Peptide Optimization on Lipase LipS Secretion and Expression in Bacillus subtilis System

DOI  NA,

Publication Year  2015

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.