SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB07102

Signal sequence   MLTFHRIIRKGWMFLLAFLLTASLFCPTGQPAKA

Length  34

Organism  Bacillus subtilis 1A751p

UniProt ID  NA,

Motif  1..34



Activity Information


Pathway  Sec

Natural/Artificial  Artificial

Subcellular location  Extracellular environment

Secretion efficiency  alpha-amylase yield: 883.35(U/mL)

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB07102.cif

Structure  SPKB07102.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3880.77494

Aliphatic index  103.5294118

Isoelectric point  11.65160089

Charge (pH=7)   4.026321984

Topological polar surface area  1350.36

Aromaticity  0.147058824

Average rotatable bonds  3.617647059

Number of hydrogen bond donors  49

Number of hydrogen bond acceptors  48

X logP energy  -5.59836

Hydropathy 



Literature Information


Title  Systematic Screening of Optimal Signal Peptides for Secretory Production of Heterologous Proteins in Bacillus subtilis

DOI  10.1021/acs.jafc.8b04183,

Publication Year  2018

PubMed ID  30463403,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.