Peptide-Information

General Information

SPKB ID SPKB07095

Signal sequence MKLRKVLTGSVLSLGLLVSASPAFA

Length 25

Organism Bacillus subtilis 1A751p

UniProt ID O31925,

Motif 1..25

Activity Information

Pathway Sec

Natural/Artificial Artificial

Subcellular location Extracellular environment

Secretion efficiency alpha-amylase yield: 1211.85(U/mL)

Type Sec/SPI

Structure Information

PDB ID NA,

Predicted Structure ID SPKB07095.cif

Structure SPKB07095.cif

Very high (pLDDT > 90)

Confident (90 > pLDDT > 70)

Low (70 > pLDDT > 50)

Very low (pLDDT < 50)

Loading PAE…

Expected Position Error (Ångströms)

Physicochemical Information

Molecular weight 2559.14914

Aliphatic index 140.4

Isoelectric point 11.82305527

Charge (pH=7) 2.99739092

Topological polar surface area 968.02

Aromaticity 0.04

Average rotatable bonds 3.4

Number of hydrogen bond donors 35

Number of hydrogen bond acceptors 35

X logP energy -8.02613

Hydropathy

Literature Information

Title Systematic Screening of Optimal Signal Peptides for Secretory Production of Heterologous Proteins in Bacillus subtilis

Publication Year 2018

PubMed ID 30463403,

Patent ID NA,