General Information
SPKB ID SPKB07089
Signal sequence MKKVMLATALFLGLTPAGANA
Length 21
Organism Bacillus subtilis 1A751p
UniProt ID P39116,
Motif 1..21
Activity Information
Pathway Sec
Natural/Artificial Artificial
Subcellular location Extracellular environment
Secretion efficiency alpha-amylase yield: 1487.85(U/mL)
Type Sec/SPI
Structure Information
PDB ID 1BN8,
Predicted Structure ID SPKB07089.cif
Physicochemical Information
Molecular weight 2118.62394
Aliphatic index 111.9047619
Isoelectric point 10.80537956
Charge (pH=7) 1.997394232
Topological polar surface area 772.12
Aromaticity 0.047619048
Average rotatable bonds 3.285714286
Number of hydrogen bond donors 26
Number of hydrogen bond acceptors 29
X logP energy -5.5529
Hydropathy
Literature Information
Title Systematic Screening of Optimal Signal Peptides for Secretory Production of Heterologous Proteins in Bacillus subtilis
Publication Year 2018
PubMed ID 30463403,
Patent ID NA,