SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB07051

Signal sequence   MDNIQTFIKESDDFKSIINGLHEGLKEQLLAGLSGSARSVFTSALAN

Length  47

Organism  Bacillus amyloliquefaciens 111018

UniProt ID  NA,

Motif  1..47



Activity Information


Pathway  Tat

Natural/Artificial  Artificial

Subcellular location  Periplasmic space

Secretion efficiency  Alkaline protease yield: 11600.9(U/mL)

Type  Tat/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB07051.cif

Structure  SPKB07051.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  5067.70244

Aliphatic index  97.65957447

Isoelectric point  4.734187638

Charge (pH=7)   -1.905330202

Topological polar surface area  2171.65

Aromaticity  0.063829787

Average rotatable bonds  3.744680851

Number of hydrogen bond donors  74

Number of hydrogen bond acceptors  73

X logP energy  -24.59033

Hydropathy 



Literature Information


Title  Engineering a highly efficient expression system to produce BcaPRO protease in Bacillus subtilis by an optimized promoter and signal peptide

DOI  10.1016/j.ijbiomac.2019.07.175,

Publication Year  2019

PubMed ID  31356949,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.