General Information
SPKB ID SPKB07016
Signal sequence MKIHTTEALMKAEISRRSLMKTSALGSLALASSAFTLPFSQMVRAA
Length 46
Organism Bacillus subtilis WB600
UniProt ID NA,
Motif 1..46
Activity Information
Pathway Tat
Natural/Artificial Artificial
Subcellular location Extracellular environment
Secretion efficiency Alkaline protease yield: 1815.64(U/mL)
Type Tat/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB07016.cif
Physicochemical Information
Molecular weight 4954.90104
Aliphatic index 91.52173913
Isoelectric point 11.65059825
Charge (pH=7) 4.0915486
Topological polar surface area 1996.69
Aromaticity 0.043478261
Average rotatable bonds 3.673913043
Number of hydrogen bond donors 73
Number of hydrogen bond acceptors 72
X logP energy -21.35929
Hydropathy
Literature Information
Title Engineering a highly efficient expression system to produce BcaPRO protease in Bacillus subtilis by an optimized promoter and signal peptide
DOI 10.1016/j.ijbiomac.2019.07.175,
Publication Year 2019
PubMed ID 31356949,
Patent ID NA,