SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB06968

Signal sequence   LSPAQRRILLYILSFIFVIGAVVYFVKSDYLFTLIFIAIAIKF

Length  43

Organism  Bacillus subtilis WB700

UniProt ID  NA,

Motif  1..43



Activity Information


Pathway  Tat

Natural/Artificial  Artificial

Subcellular location  Periplasmic space

Secretion efficiency  Alkaline active xylanase yield: 0.5(U/mL)

Type  Tat/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB06968.cif

Structure  SPKB06968.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  4984.13084

Aliphatic index  163.255814

Isoelectric point  10.17656942

Charge (pH=7)   2.995282851

Topological polar surface area  1674.57

Aromaticity  0.209302326

Average rotatable bonds  3.697674419

Number of hydrogen bond donors  60

Number of hydrogen bond acceptors  57

X logP energy  -0.56996

Hydropathy 



Literature Information


Title  Optimal secretion of alkali-tolerant xylanase in Bacillus subtilis by signal peptide screening

DOI  10.1007/s00253-016-7615-4,

Publication Year  2016

PubMed ID  27225471,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.