SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB06959

Signal sequence   MSPFPLRLCFSKIQEAVFYFFLLIMIKRRKRRRARDIG

Length  38

Organism  Bacillus subtilis WB700

UniProt ID  NA,

Motif  1..38



Activity Information


Pathway  Tat

Natural/Artificial  Artificial

Subcellular location  Periplasmic space

Secretion efficiency  Alkaline active xylanase yield: 4.7(U/mL)

Type  Tat/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB06959.cif

Structure  SPKB06959.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  4704.77494

Aliphatic index  95

Isoelectric point  12.14364855

Charge (pH=7)   7.936472495

Topological polar surface area  1812.18

Aromaticity  0.157894737

Average rotatable bonds  4.184210526

Number of hydrogen bond donors  68

Number of hydrogen bond acceptors  58

X logP energy  -9.53841

Hydropathy 



Literature Information


Title  Optimal secretion of alkali-tolerant xylanase in Bacillus subtilis by signal peptide screening

DOI  10.1007/s00253-016-7615-4,

Publication Year  2016

PubMed ID  27225471,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.