SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB06950

Signal sequence   MKKRRKICYCNTALLLMILLAGGCT

Length  25

Organism  Bacillus subtilis WB700

UniProt ID  NA,

Motif  1..25



Activity Information


Pathway  Tat

Natural/Artificial  Artificial

Subcellular location  Periplasmic space

Secretion efficiency  Alkaline active xylanase yield: 19.5(U/mL)

Type  Tat/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB06950.cif

Structure  SPKB06950.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2814.58134

Aliphatic index  117.2

Isoelectric point  10.15364277

Charge (pH=7)   4.810318013

Topological polar surface area  1067.36

Aromaticity  0.04

Average rotatable bonds  3.92

Number of hydrogen bond donors  42

Number of hydrogen bond acceptors  40

X logP energy  -7.54676

Hydropathy 



Literature Information


Title  Optimal secretion of alkali-tolerant xylanase in Bacillus subtilis by signal peptide screening

DOI  10.1007/s00253-016-7615-4,

Publication Year  2016

PubMed ID  27225471,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.