SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB06946

Signal sequence   MVSIRRSFEAYVDDMNIITVLIPPAEEKEIM

Length  31

Organism  Bacillus subtilis WB700

UniProt ID  NA,

Motif  1..31



Activity Information


Pathway  Tat

Natural/Artificial  Artificial

Subcellular location  Periplasmic space

Secretion efficiency  Alkaline active xylanase yield: 30.9(U/mL)

Type  Tat/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB06946.cif

Structure  SPKB06946.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3611.24444

Aliphatic index  110

Isoelectric point  4.103657336

Charge (pH=7)   -2.995174312

Topological polar surface area  1416.37

Aromaticity  0.064516129

Average rotatable bonds  3.870967742

Number of hydrogen bond donors  48

Number of hydrogen bond acceptors  49

X logP energy  -9.00566

Hydropathy 



Literature Information


Title  Optimal secretion of alkali-tolerant xylanase in Bacillus subtilis by signal peptide screening

DOI  10.1007/s00253-016-7615-4,

Publication Year  2016

PubMed ID  27225471,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.