SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB06937

Signal sequence   MMIKQCVICLSLLVFGTTAAHA

Length  22

Organism  Bacillus subtilis WB700

UniProt ID  O32019,

Motif  1..22



Activity Information


Pathway  Sec

Natural/Artificial  Artificial

Subcellular location  Extracellular environment

Secretion efficiency  Alkaline active xylanase yield: 46.9(U/mL)

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB06937.cif

Structure  SPKB06937.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2350.93944

Aliphatic index  128.6363636

Isoelectric point  8.241247528

Charge (pH=7)   0.964648925

Topological polar surface area  832.9

Aromaticity  0.045454545

Average rotatable bonds  3.5

Number of hydrogen bond donors  31

Number of hydrogen bond acceptors  33

X logP energy  -5.4646

Hydropathy 



Literature Information


Title  Optimal secretion of alkali-tolerant xylanase in Bacillus subtilis by signal peptide screening

DOI  10.1007/s00253-016-7615-4,

Publication Year  2016

PubMed ID  27225471,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.