SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB06925

Signal sequence   MRKKRVITCVMAASLTLGSLLPAGYATA

Length  28

Organism  Bacillus subtilis WB700

UniProt ID  O31973,

Motif  1..28



Activity Information


Pathway  Sec

Natural/Artificial  Artificial

Subcellular location  Extracellular environment

Secretion efficiency  Alkaline active xylanase yield: 77.2(U/mL)

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB06925.cif

Structure  SPKB06925.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2923.58684

Aliphatic index  108.2142857

Isoelectric point  10.88840969

Charge (pH=7)   3.934562479

Topological polar surface area  1137.45

Aromaticity  0.035714286

Average rotatable bonds  3.428571429

Number of hydrogen bond donors  43

Number of hydrogen bond acceptors  42

X logP energy  -10.80526

Hydropathy 



Literature Information


Title  Optimal secretion of alkali-tolerant xylanase in Bacillus subtilis by signal peptide screening

DOI  10.1007/s00253-016-7615-4,

Publication Year  2016

PubMed ID  27225471,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.