SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB06903

Signal sequence   MKKRLIAPMLLSAASLAFFAMSGSAQA

Length  27

Organism  Bacillus subtilis WB700

UniProt ID  P39848,

Motif  1..27



Activity Information


Pathway  Sec

Natural/Artificial  Artificial

Subcellular location  Extracellular environment

Secretion efficiency  Alkaline active xylanase yield: 111(U/mL)

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB06903.cif

Structure  SPKB06903.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2812.44264

Aliphatic index  98.14814815

Isoelectric point  11.82305527

Charge (pH=7)   2.99739092

Topological polar surface area  1049.08

Aromaticity  0.074074074

Average rotatable bonds  3.481481481

Number of hydrogen bond donors  37

Number of hydrogen bond acceptors  39

X logP energy  -8.98883

Hydropathy 



Literature Information


Title  Optimal secretion of alkali-tolerant xylanase in Bacillus subtilis by signal peptide screening

DOI  10.1007/s00253-016-7615-4,

Publication Year  2016

PubMed ID  27225471,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.