SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB06895

Signal sequence   MKKTLTTIRRSSIARRLIISFLLILIVPITALSVSAYQS

Length  39

Organism  Bacillus subtilis WB700

UniProt ID  NA,

Motif  1..39



Activity Information


Pathway  Tat

Natural/Artificial  Artificial

Subcellular location  Periplasmic space

Secretion efficiency  Alkaline active xylanase yield: 125.5(U/mL)

Type  Tat/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB06895.cif

Structure  SPKB06895.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  4375.36944

Aliphatic index  152.5641026

Isoelectric point  12.51802133

Charge (pH=7)   5.996530572

Topological polar surface area  1725.59

Aromaticity  0.051282051

Average rotatable bonds  3.794871795

Number of hydrogen bond donors  65

Number of hydrogen bond acceptors  59

X logP energy  -13.70442

Hydropathy 



Literature Information


Title  Optimal secretion of alkali-tolerant xylanase in Bacillus subtilis by signal peptide screening

DOI  10.1007/s00253-016-7615-4,

Publication Year  2016

PubMed ID  27225471,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.