SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB06892

Signal sequence   MKKMLMLAFTFLLALTIHVGEASA

Length  24

Organism  Bacillus subtilis WB700

UniProt ID  O34541,

Motif  1..24



Activity Information


Pathway  Sec

Natural/Artificial  Artificial

Subcellular location  Extracellular environment

Secretion efficiency  Alkaline active xylanase yield: 133.9(U/mL)

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB06892.cif

Structure  SPKB06892.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2637.29554

Aliphatic index  126.25

Isoelectric point  9.539374794

Charge (pH=7)   1.090078445

Topological polar surface area  911.33

Aromaticity  0.083333333

Average rotatable bonds  3.708333333

Number of hydrogen bond donors  32

Number of hydrogen bond acceptors  35

X logP energy  -3.2205

Hydropathy 



Literature Information


Title  Optimal secretion of alkali-tolerant xylanase in Bacillus subtilis by signal peptide screening

DOI  10.1007/s00253-016-7615-4,

Publication Year  2016

PubMed ID  27225471,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.