SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB06891

Signal sequence   MKRLCLWFTVFSLFLVLLPGKALG

Length  24

Organism  Bacillus subtilis WB700

UniProt ID  O34819,

Motif  1..24



Activity Information


Pathway  Sec

Natural/Artificial  Artificial

Subcellular location  Extracellular environment

Secretion efficiency  Alkaline active xylanase yield: 134.9(U/mL)

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB06891.cif

Structure  SPKB06891.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2753.48894

Aliphatic index  142.0833333

Isoelectric point  10.79319833

Charge (pH=7)   2.935416204

Topological polar surface area  894.02

Aromaticity  0.166666667

Average rotatable bonds  3.666666667

Number of hydrogen bond donors  33

Number of hydrogen bond acceptors  32

X logP energy  0.00167

Hydropathy 



Literature Information


Title  Optimal secretion of alkali-tolerant xylanase in Bacillus subtilis by signal peptide screening

DOI  10.1007/s00253-016-7615-4,

Publication Year  2016

PubMed ID  27225471,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.