SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB06890

Signal sequence   MNIKKFAKQATVLTFTTALLAGGATQAFA

Length  29

Organism  Bacillus subtilis WB700

UniProt ID  P05655,

Motif  1..29



Activity Information


Pathway  Sec

Natural/Artificial  Artificial

Subcellular location  Extracellular environment

Secretion efficiency  Alkaline active xylanase yield: 135.5(U/mL)

Type  Sec/SPI



Structure Information


PDB ID  3BYJ,

Predicted Structure ID  SPKB06890.cif

Structure  SPKB06890.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3014.57624

Aliphatic index  87.93103448

Isoelectric point  11.10307074

Charge (pH=7)   2.997099198

Topological polar surface area  1186.6

Aromaticity  0.103448276

Average rotatable bonds  3.448275862

Number of hydrogen bond donors  41

Number of hydrogen bond acceptors  42

X logP energy  -11.6062

Hydropathy 



Literature Information


Title  Optimal secretion of alkali-tolerant xylanase in Bacillus subtilis by signal peptide screening

DOI  10.1007/s00253-016-7615-4,

Publication Year  2016

PubMed ID  27225471,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.