SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB06888

Signal sequence   MKKIGLLFMLCLAALFTIGFPAQQADA

Length  27

Organism  Bacillus subtilis WB700

UniProt ID  O31737,

Motif  1..27



Activity Information


Pathway  Sec

Natural/Artificial  Artificial

Subcellular location  Extracellular environment

Secretion efficiency  Alkaline active xylanase yield: 138.2(U/mL)

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB06888.cif

Structure  SPKB06888.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2912.60264

Aliphatic index  119.6296296

Isoelectric point  8.540492971

Charge (pH=7)   0.935866

Topological polar surface area  1006.88

Aromaticity  0.111111111

Average rotatable bonds  3.555555556

Number of hydrogen bond donors  34

Number of hydrogen bond acceptors  37

X logP energy  -3.9971

Hydropathy 



Literature Information


Title  Optimal secretion of alkali-tolerant xylanase in Bacillus subtilis by signal peptide screening

DOI  10.1007/s00253-016-7615-4,

Publication Year  2016

PubMed ID  27225471,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.