SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB06886

Signal sequence   MKKRITYSLLALLAVVAFAFTDSSKAKA

Length  28

Organism  Bacillus subtilis WB700

UniProt ID  O31994,

Motif  1..28



Activity Information


Pathway  Sec

Natural/Artificial  Artificial

Subcellular location  Extracellular environment

Secretion efficiency  Alkaline active xylanase yield: 142.1(U/mL)

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB06886.cif

Structure  SPKB06886.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3044.68934

Aliphatic index  111.7857143

Isoelectric point  10.85742466

Charge (pH=7)   3.996396923

Topological polar surface area  1173.68

Aromaticity  0.107142857

Average rotatable bonds  3.678571429

Number of hydrogen bond donors  43

Number of hydrogen bond acceptors  42

X logP energy  -8.67093

Hydropathy 



Literature Information


Title  Optimal secretion of alkali-tolerant xylanase in Bacillus subtilis by signal peptide screening

DOI  10.1007/s00253-016-7615-4,

Publication Year  2016

PubMed ID  27225471,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.