SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB06881

Signal sequence   MKWMCSICCAAVLLAGGAAQA

Length  21

Organism  Bacillus subtilis WB700

UniProt ID  NA,

Motif  1..21



Activity Information


Pathway  Sec

Natural/Artificial  Artificial

Subcellular location  Extracellular environment

Secretion efficiency  Alkaline active xylanase yield: 151.2(U/mL)

Type  Sec/SPI



Structure Information


PDB ID  1W17,

Predicted Structure ID  SPKB06881.cif

Structure  SPKB06881.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2098.60044

Aliphatic index  98.0952381

Isoelectric point  8.045790785

Charge (pH=7)   0.811765118

Topological polar surface area  750.45

Aromaticity  0.047619048

Average rotatable bonds  3.19047619

Number of hydrogen bond donors  29

Number of hydrogen bond acceptors  30

X logP energy  -6.3228

Hydropathy 



Literature Information


Title  Optimal secretion of alkali-tolerant xylanase in Bacillus subtilis by signal peptide screening

DOI  10.1007/s00253-016-7615-4,

Publication Year  2016

PubMed ID  27225471,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.