SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB06876

Signal sequence   MKLVPRFRKQWFAYLTVLCLALAAAVSFGVPAKA

Length  34

Organism  Bacillus subtilis WB700

UniProt ID  P39790,

Motif  1..34



Activity Information


Pathway  Sec

Natural/Artificial  Artificial

Subcellular location  Extracellular environment

Secretion efficiency  Alkaline active xylanase yield: 161.7(U/mL)

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB06876.cif

Structure  SPKB06876.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3767.64124

Aliphatic index  112.0588235

Isoelectric point  11.11134211

Charge (pH=7)   4.934267445

Topological polar surface area  1327.47

Aromaticity  0.147058824

Average rotatable bonds  3.470588235

Number of hydrogen bond donors  48

Number of hydrogen bond acceptors  46

X logP energy  -5.33026

Hydropathy 



Literature Information


Title  Optimal secretion of alkali-tolerant xylanase in Bacillus subtilis by signal peptide screening

DOI  10.1007/s00253-016-7615-4,

Publication Year  2016

PubMed ID  27225471,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.