SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB06870

Signal sequence   MFKFKKNFLVGLSAALMSISLFSATASA

Length  28

Organism  Bacillus subtilis WB700

UniProt ID  P18429,

Motif  1..28



Activity Information


Pathway  Sec

Natural/Artificial  Artificial

Subcellular location  Extracellular environment

Secretion efficiency  Alkaline active xylanase yield: 181.2(U/mL)

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB06870.cif

Structure  SPKB06870.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2981.60454

Aliphatic index  97.85714286

Isoelectric point  11.10307074

Charge (pH=7)   2.997099198

Topological polar surface area  1091.55

Aromaticity  0.142857143

Average rotatable bonds  3.571428571

Number of hydrogen bond donors  39

Number of hydrogen bond acceptors  41

X logP energy  -8.813

Hydropathy 



Literature Information


Title  Optimal secretion of alkali-tolerant xylanase in Bacillus subtilis by signal peptide screening

DOI  10.1007/s00253-016-7615-4,

Publication Year  2016

PubMed ID  27225471,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.