SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB06869

Signal sequence   MRKTIFAFLTGLMMFGTITAASA

Length  23

Organism  Bacillus subtilis WB700

UniProt ID  P40407,

Motif  1..23



Activity Information


Pathway  Sec

Natural/Artificial  Artificial

Subcellular location  Extracellular environment

Secretion efficiency  Alkaline active xylanase yield: 188.9(U/mL)

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB06869.cif

Structure  SPKB06869.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2480.03964

Aliphatic index  85.2173913

Isoelectric point  11.65177567

Charge (pH=7)   1.997685954

Topological polar surface area  892.59

Aromaticity  0.130434783

Average rotatable bonds  3.52173913

Number of hydrogen bond donors  33

Number of hydrogen bond acceptors  34

X logP energy  -6.51413

Hydropathy 



Literature Information


Title  Optimal secretion of alkali-tolerant xylanase in Bacillus subtilis by signal peptide screening

DOI  10.1007/s00253-016-7615-4,

Publication Year  2016

PubMed ID  27225471,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.