SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB06855

Signal sequence   MKNRLFILICFCVICLFLSFGQPFFPSMILTVQAAKS

Length  37

Organism  Bacillus subtilis WB700

UniProt ID  NA,

Motif  1..37



Activity Information


Pathway  Sec

Natural/Artificial  Artificial

Subcellular location  Extracellular environment

Secretion efficiency  Alkaline active xylanase yield: 270.9(U/mL)

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB06855.cif

Structure  SPKB06855.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  4228.25974

Aliphatic index  115.9459459

Isoelectric point  8.985664248

Charge (pH=7)   2.811466773

Topological polar surface area  1417.47

Aromaticity  0.162162162

Average rotatable bonds  3.675675676

Number of hydrogen bond donors  51

Number of hydrogen bond acceptors  53

X logP energy  -5.70123

Hydropathy 



Literature Information


Title  Optimal secretion of alkali-tolerant xylanase in Bacillus subtilis by signal peptide screening

DOI  10.1007/s00253-016-7615-4,

Publication Year  2016

PubMed ID  27225471,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.