SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB06851

Signal sequence   MKLFNRKVTLVSLILMAVFQFFMALIIKRIVIS

Length  33

Organism  Corynebacterium glutamicum

UniProt ID  NA,

Motif  1..33



Activity Information


Pathway  Sec

Natural/Artificial  Artificial

Subcellular location  Extracellular environment

Secretion efficiency  Cutinase yield: 0.4(U/mL)

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB06851.cif

Structure  SPKB06851.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3884.97474

Aliphatic index  159.3939394

Isoelectric point  12.54607567

Charge (pH=7)   4.997092575

Topological polar surface area  1343.25

Aromaticity  0.121212121

Average rotatable bonds  4.060606061

Number of hydrogen bond donors  48

Number of hydrogen bond acceptors  47

X logP energy  -2.31336

Hydropathy 



Literature Information


Title  Use of a Sec signal peptide library from Bacillus subtilis for the optimization of cutinase secretion in Corynebacterium glutamicum

DOI  10.1186/s12934-016-0604-6,

Publication Year  2016

PubMed ID  27927208,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.