SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB06825

Signal sequence   MKISMQKADFWKKAAISLLVFTMFFTLMMSETVFA

Length  35

Organism  Corynebacterium glutamicum

UniProt ID  NA,

Motif  1..35



Activity Information


Pathway  Sec

Natural/Artificial  Artificial

Subcellular location  Extracellular environment

Secretion efficiency  Cutinase yield: 7.5(U/mL)

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB06825.cif

Structure  SPKB06825.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  4094.03294

Aliphatic index  83.71428571

Isoelectric point  10.333323

Charge (pH=7)   1.999025771

Topological polar surface area  1411.66

Aromaticity  0.171428571

Average rotatable bonds  3.942857143

Number of hydrogen bond donors  50

Number of hydrogen bond acceptors  54

X logP energy  -5.5531

Hydropathy 



Literature Information


Title  Use of a Sec signal peptide library from Bacillus subtilis for the optimization of cutinase secretion in Corynebacterium glutamicum

DOI  10.1186/s12934-016-0604-6,

Publication Year  2016

PubMed ID  27927208,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.