SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB06822

Signal sequence   MKRITINIITMFIAAAVISLTGTAEA

Length  26

Organism  Corynebacterium glutamicum

UniProt ID  NA,

Motif  1..26



Activity Information


Pathway  Sec

Natural/Artificial  Artificial

Subcellular location  Extracellular environment

Secretion efficiency  Cutinase yield: 8.5(U/mL)

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB06822.cif

Structure  SPKB06822.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2750.35084

Aliphatic index  135.3846154

Isoelectric point  9.695027686

Charge (pH=7)   0.999461077

Topological polar surface area  1060.28

Aromaticity  0.038461538

Average rotatable bonds  3.538461538

Number of hydrogen bond donors  38

Number of hydrogen bond acceptors  38

X logP energy  -8.37523

Hydropathy 



Literature Information


Title  Use of a Sec signal peptide library from Bacillus subtilis for the optimization of cutinase secretion in Corynebacterium glutamicum

DOI  10.1186/s12934-016-0604-6,

Publication Year  2016

PubMed ID  27927208,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.