General Information
SPKB ID SPKB06809
Signal sequence MKKRLSFISLMLIFTLVLSA
Length 20
Organism Bacillus licheniformis strain 3F-3
UniProt ID NA,
Motif 1..20
Activity Information
Pathway Sec
Natural/Artificial Artificial
Subcellular location Cell membrane
Secretion efficiency Nattokinase yield: 2.95(FU/mL)
Type Sec/SPII
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06809.cif
Physicochemical Information
Molecular weight 2311.95624
Aliphatic index 156
Isoelectric point 11.82305527
Charge (pH=7) 2.99739092
Topological polar surface area 811.08
Aromaticity 0.1
Average rotatable bonds 4
Number of hydrogen bond donors 30
Number of hydrogen bond acceptors 30
X logP energy -2.52133
Hydropathy 
Literature Information
Title High-level expression of nattokinase in Bacillus licheniformis by manipulating signal peptide and signal peptidase
DOI 10.1111/jam.13175,
Publication Year 2016
PubMed ID 27159567,
Patent ID NA,
