General Information
SPKB ID SPKB06796
Signal sequence MNMRKCFIQVLALLFIIAACFAPNQASA
Length 28
Organism Bacillus licheniformis strain 3F-3
UniProt ID NA,
Motif 1..28
Activity Information
Pathway Sec
Natural/Artificial Artificial
Subcellular location Extracellular environment
Secretion efficiency Nattokinase yield: 3.63(FU/mL)
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06796.cif
Physicochemical Information
Molecular weight 3085.79514
Aliphatic index 115.3571429
Isoelectric point 8.828181491
Charge (pH=7) 1.873736522
Topological polar surface area 1120.74
Aromaticity 0.107142857
Average rotatable bonds 3.571428571
Number of hydrogen bond donors 39
Number of hydrogen bond acceptors 40
X logP energy -7.19363
Hydropathy 
Literature Information
Title High-level expression of nattokinase in Bacillus licheniformis by manipulating signal peptide and signal peptidase
DOI 10.1111/jam.13175,
Publication Year 2016
PubMed ID 27159567,
Patent ID NA,
