General Information
SPKB ID SPKB06794
Signal sequence MKKLWKIAVSAAMFVGFFANSPRIQA
Length 26
Organism Bacillus licheniformis strain 3F-3
UniProt ID NA,
Motif 1..26
Activity Information
Pathway Sec
Natural/Artificial Artificial
Subcellular location Extracellular environment
Secretion efficiency Nattokinase yield: 3.67(FU/mL)
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06794.cif
Physicochemical Information
Molecular weight 2912.55014
Aliphatic index 86.53846154
Isoelectric point 11.92450937
Charge (pH=7) 3.997095887
Topological polar surface area 1064.42
Aromaticity 0.153846154
Average rotatable bonds 3.653846154
Number of hydrogen bond donors 37
Number of hydrogen bond acceptors 37
X logP energy -6.06023
Hydropathy 
Literature Information
Title High-level expression of nattokinase in Bacillus licheniformis by manipulating signal peptide and signal peptidase
DOI 10.1111/jam.13175,
Publication Year 2016
PubMed ID 27159567,
Patent ID NA,
