SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB06790

Signal sequence   MRQVSKKTAPSVAYLLTKAACFFVLCLILLYVWDLSQSSA

Length  40

Organism  Bacillus licheniformis strain 3F-3

UniProt ID  NA,

Motif  1..40



Activity Information


Pathway  NA

Natural/Artificial  Artificial

Subcellular location  Extracellular environment

Secretion efficiency  Nattokinase yield: 3.75(FU/mL)

Type  NA



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB06790.cif

Structure  SPKB06790.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  4466.38114

Aliphatic index  119.5

Isoelectric point  9.345704458

Charge (pH=7)   2.87189211

Topological polar surface area  1650.73

Aromaticity  0.125

Average rotatable bonds  3.6

Number of hydrogen bond donors  61

Number of hydrogen bond acceptors  60

X logP energy  -10.99823

Hydropathy 



Literature Information


Title  High-level expression of nattokinase in Bacillus licheniformis by manipulating signal peptide and signal peptidase

DOI  10.1111/jam.13175,

Publication Year  2016

PubMed ID  27159567,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.