General Information
SPKB ID SPKB06786
Signal sequence MNGKYKYVTIASLLSAAVLLGTG
Length 23
Organism Bacillus licheniformis strain 3F-3
UniProt ID NA,
Motif 1..23
Activity Information
Pathway Sec
Natural/Artificial Artificial
Subcellular location Cell membrane
Secretion efficiency Nattokinase yield: 4.03(FU/mL)
Type Sec/SPII
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06786.cif
Physicochemical Information
Molecular weight 2370.83274
Aliphatic index 123.0434783
Isoelectric point 9.930129002
Charge (pH=7) 1.995693403
Topological polar surface area 920.03
Aromaticity 0.086956522
Average rotatable bonds 3.391304348
Number of hydrogen bond donors 33
Number of hydrogen bond acceptors 34
X logP energy -7.9104
Hydropathy 
Literature Information
Title High-level expression of nattokinase in Bacillus licheniformis by manipulating signal peptide and signal peptidase
DOI 10.1111/jam.13175,
Publication Year 2016
PubMed ID 27159567,
Patent ID NA,
