General Information
SPKB ID SPKB06785
Signal sequence MKKRMIQMGIIGAMMFPEAFSA
Length 22
Organism Bacillus licheniformis strain 3F-3
UniProt ID NA,
Motif 1..22
Activity Information
Pathway Sec
Natural/Artificial Artificial
Subcellular location Extracellular environment
Secretion efficiency Nattokinase yield: 4.16(FU/mL)
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06785.cif
Physicochemical Information
Molecular weight 2489.12664
Aliphatic index 66.81818182
Isoelectric point 10.7890093
Charge (pH=7) 1.999166043
Topological polar surface area 880.19
Aromaticity 0.090909091
Average rotatable bonds 3.909090909
Number of hydrogen bond donors 30
Number of hydrogen bond acceptors 34
X logP energy -4.55913
Hydropathy 
Literature Information
Title High-level expression of nattokinase in Bacillus licheniformis by manipulating signal peptide and signal peptidase
DOI 10.1111/jam.13175,
Publication Year 2016
PubMed ID 27159567,
Patent ID NA,
