General Information
SPKB ID SPKB06776
Signal sequence MKSKWSAMVVIAGLLLLAG
Length 19
Organism Bacillus licheniformis strain 3F-3
UniProt ID NA,
Motif 1..19
Activity Information
Pathway NA
Natural/Artificial Artificial
Subcellular location Extracellular environment
Secretion efficiency Nattokinase yield: 4.52(FU/mL)
Type NA
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06776.cif
Physicochemical Information
Molecular weight 1988.52064
Aliphatic index 148.9473684
Isoelectric point 10.80537956
Charge (pH=7) 1.997394232
Topological polar surface area 695.41
Aromaticity 0.052631579
Average rotatable bonds 3.526315789
Number of hydrogen bond donors 25
Number of hydrogen bond acceptors 26
X logP energy -2.5375
Hydropathy 
Literature Information
Title High-level expression of nattokinase in Bacillus licheniformis by manipulating signal peptide and signal peptidase
DOI 10.1111/jam.13175,
Publication Year 2016
PubMed ID 27159567,
Patent ID NA,
