General Information
SPKB ID SPKB06767
Signal sequence MKNIRKTVIFAAIILLVHTAVPA
Length 23
Organism Bacillus licheniformis strain 3F-3
UniProt ID NA,
Motif 1..23
Activity Information
Pathway Sec
Natural/Artificial Artificial
Subcellular location Extracellular environment
Secretion efficiency Nattokinase yield: 5.16(FU/mL)
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06767.cif
Physicochemical Information
Molecular weight 2520.16134
Aliphatic index 156.9565217
Isoelectric point 11.82306209
Charge (pH=7) 3.088300011
Topological polar surface area 920.9
Aromaticity 0.043478261
Average rotatable bonds 3.565217391
Number of hydrogen bond donors 32
Number of hydrogen bond acceptors 32
X logP energy -3.98583
Hydropathy 
Literature Information
Title High-level expression of nattokinase in Bacillus licheniformis by manipulating signal peptide and signal peptidase
DOI 10.1111/jam.13175,
Publication Year 2016
PubMed ID 27159567,
Patent ID NA,
