General Information
SPKB ID SPKB06761
Signal sequence MMKRLAGTVILSGLLVCGFGQALPEKALA
Length 29
Organism Bacillus licheniformis strain 3F-3
UniProt ID NA,
Motif 1..29
Activity Information
Pathway Sec
Natural/Artificial Artificial
Subcellular location Extracellular environment
Secretion efficiency Nattokinase yield: 5.73(FU/mL)
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06761.cif
Physicochemical Information
Molecular weight 2988.70154
Aliphatic index 127.9310345
Isoelectric point 9.673754512
Charge (pH=7) 1.937191327
Topological polar surface area 1104.12
Aromaticity 0.034482759
Average rotatable bonds 3.482758621
Number of hydrogen bond donors 39
Number of hydrogen bond acceptors 40
X logP energy -7.57783
Hydropathy 
Literature Information
Title High-level expression of nattokinase in Bacillus licheniformis by manipulating signal peptide and signal peptidase
DOI 10.1111/jam.13175,
Publication Year 2016
PubMed ID 27159567,
Patent ID NA,
