General Information
SPKB ID SPKB06758
Signal sequence MGFLRNRIVGITLAGAVALGSAGTGSA
Length 27
Organism Bacillus licheniformis strain 3F-3
UniProt ID NA,
Motif 1..27
Activity Information
Pathway Sec
Natural/Artificial Artificial
Subcellular location Extracellular environment
Secretion efficiency Nattokinase yield: 5.92(FU/mL)
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06758.cif
Physicochemical Information
Molecular weight 2560.99744
Aliphatic index 112.2222222
Isoelectric point 12.50010931
Charge (pH=7) 1.997977677
Topological polar surface area 1067.73
Aromaticity 0.037037037
Average rotatable bonds 3.111111111
Number of hydrogen bond donors 39
Number of hydrogen bond acceptors 36
X logP energy -13.42256
Hydropathy 
Literature Information
Title High-level expression of nattokinase in Bacillus licheniformis by manipulating signal peptide and signal peptidase
DOI 10.1111/jam.13175,
Publication Year 2016
PubMed ID 27159567,
Patent ID NA,
