General Information
SPKB ID SPKB06757
Signal sequence MKAPVRYIWIGMILCFLSVSLAVGCIKA
Length 28
Organism Bacillus licheniformis strain 3F-3
UniProt ID NA,
Motif 1..28
Activity Information
Pathway Sec
Natural/Artificial Artificial
Subcellular location Cell membrane
Secretion efficiency Nattokinase yield: 6.03(FU/mL)
Type Sec/SPII
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06757.cif
Physicochemical Information
Molecular weight 3083.90644
Aliphatic index 139.2857143
Isoelectric point 9.496995431
Charge (pH=7) 2.872591074
Topological polar surface area 1030.65
Aromaticity 0.107142857
Average rotatable bonds 3.535714286
Number of hydrogen bond donors 39
Number of hydrogen bond acceptors 39
X logP energy -2.60603
Hydropathy 
Literature Information
Title High-level expression of nattokinase in Bacillus licheniformis by manipulating signal peptide and signal peptidase
DOI 10.1111/jam.13175,
Publication Year 2016
PubMed ID 27159567,
Patent ID NA,
