General Information
SPKB ID SPKB06752
Signal sequence MKKFACVVIFLLLAAVIAG
Length 19
Organism Bacillus licheniformis strain 3F-3
UniProt ID NA,
Motif 1..19
Activity Information
Pathway Sec
Natural/Artificial Artificial
Subcellular location Cell membrane
Secretion efficiency Nattokinase yield: 6.48(FU/mL)
Type Sec/SPII
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06752.cif
Physicochemical Information
Molecular weight 2007.60994
Aliphatic index 169.4736842
Isoelectric point 9.676237541
Charge (pH=7) 1.935419516
Topological polar surface area 639.16
Aromaticity 0.105263158
Average rotatable bonds 3.473684211
Number of hydrogen bond donors 23
Number of hydrogen bond acceptors 24
X logP energy 0.4605
Hydropathy 
Literature Information
Title High-level expression of nattokinase in Bacillus licheniformis by manipulating signal peptide and signal peptidase
DOI 10.1111/jam.13175,
Publication Year 2016
PubMed ID 27159567,
Patent ID NA,
