General Information
SPKB ID SPKB06751
Signal sequence MKMWMRKALVALFTIATFGLVSPPAALMA
Length 29
Organism Bacillus licheniformis strain 3F-3
UniProt ID NA,
Motif 1..29
Activity Information
Pathway Sec
Natural/Artificial Artificial
Subcellular location Extracellular environment
Secretion efficiency Nattokinase yield: 6.54(FU/mL)
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06751.cif
Physicochemical Information
Molecular weight 3166.99644
Aliphatic index 107.9310345
Isoelectric point 11.82305527
Charge (pH=7) 2.99739092
Topological polar surface area 1050.96
Aromaticity 0.103448276
Average rotatable bonds 3.448275862
Number of hydrogen bond donors 37
Number of hydrogen bond acceptors 40
X logP energy -3.22463
Hydropathy 
Literature Information
Title High-level expression of nattokinase in Bacillus licheniformis by manipulating signal peptide and signal peptidase
DOI 10.1111/jam.13175,
Publication Year 2016
PubMed ID 27159567,
Patent ID NA,
