General Information
SPKB ID SPKB06749
Signal sequence MNIKNIAKKASALTVAAALLAGGAPQTFA
Length 29
Organism Bacillus licheniformis strain 3F-3
UniProt ID NA,
Motif 1..29
Activity Information
Pathway Sec
Natural/Artificial Artificial
Subcellular location Extracellular environment
Secretion efficiency Nattokinase yield: 6.57(FU/mL)
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06749.cif
Physicochemical Information
Molecular weight 2842.39274
Aliphatic index 108.2758621
Isoelectric point 11.10307074
Charge (pH=7) 2.997099198
Topological polar surface area 1137.35
Aromaticity 0.034482759
Average rotatable bonds 3.24137931
Number of hydrogen bond donors 38
Number of hydrogen bond acceptors 40
X logP energy -12.0397
Hydropathy 
Literature Information
Title High-level expression of nattokinase in Bacillus licheniformis by manipulating signal peptide and signal peptidase
DOI 10.1111/jam.13175,
Publication Year 2016
PubMed ID 27159567,
Patent ID NA,
