General Information
SPKB ID SPKB06741
Signal sequence MNRKCVIPFILMLSAMCAPAQNAEA
Length 25
Organism Bacillus licheniformis strain 3F-3
UniProt ID NA,
Motif 1..25
Activity Information
Pathway Sec
Natural/Artificial Artificial
Subcellular location Extracellular environment
Secretion efficiency Nattokinase yield: 9.05(FU/mL)
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06741.cif
Physicochemical Information
Molecular weight 2723.33844
Aliphatic index 94
Isoelectric point 8.22970453
Charge (pH=7) 0.875511645
Topological polar surface area 1018.86
Aromaticity 0.04
Average rotatable bonds 3.52
Number of hydrogen bond donors 35
Number of hydrogen bond acceptors 38
X logP energy -8.38693
Hydropathy 
Literature Information
Title High-level expression of nattokinase in Bacillus licheniformis by manipulating signal peptide and signal peptidase
DOI 10.1111/jam.13175,
Publication Year 2016
PubMed ID 27159567,
Patent ID NA,
